DNM2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DNM2	ENSG00000079805	T-ALL	No drugs in record	GTPase activity protein binding GTP binding microtubule binding SH3 domain binding enzyme binding protein kinase binding D2 dopamine receptor binding protein complex binding phosphatidylinositol 3-kinase regulatory subunit binding WW domain binding nitric-oxide synthase binding	VPS1 (S. cerevisiae) dyn-1 (C. elegans) shi (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)