SNX1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SNX1	ENSG00000028528	No diseases in record	No drugs in record	epidermal growth factor receptor binding insulin receptor binding protein binding phosphatidylinositol binding identical protein binding protein homodimerization activity protein heterodimerization activity cadherin binding involved in cell-cell adhesion transferrin receptor binding leptin receptor binding protein transporter activity phosphatidylinositol-3-phosphate binding	VPS5 (S. cerevisiae) snx-1 (C. elegans) Snx1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)