AURKB - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AURKB	ENSG00000178999	No diseases in record	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding histone serine kinase activity metal ion binding	IPL1 (S. cerevisiae) air-2 (C. elegans) aurA (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)