TOP1 - VAMP2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
VAMP2	ENSG00000220205	No diseases in record	BOTULINUM TOXIN TYPE B	SNARE binding SNAP receptor activity protein binding calmodulin binding phospholipid binding syntaxin-1 binding syntaxin binding protein self-association calcium-dependent protein binding	SNC1 (S. cerevisiae) SNC2 (S. cerevisiae) snb-1 (C. elegans) Syb (D. melanogaster) nSyb (D. melanogaster)