NIPBL - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NIPBL	ENSG00000164190	No diseases in record	No drugs in record	chromatin binding protein binding protein C-terminus binding mediator complex binding histone deacetylase binding protein N-terminus binding chromo shadow domain binding	SCC2 (S. cerevisiae) Nipped-B (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)