SMC6 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMC6	ENSG00000163029	No diseases in record	No drugs in record	protein binding ATP binding ubiquitin protein ligase binding SUMO transferase activity damaged DNA binding nucleotide binding double-stranded DNA-dependent ATPase activity	SMC6 (S. cerevisiae) smc-6 (C. elegans) C23H4.6 (C. elegans) jnj (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)