Gene Name | Gene ID | Diseases | Drugs | GO terms | Orthologs |
---|---|---|---|---|---|
POLH | ENSG00000170734 |
No diseases in record |
No drugs in record |
damaged DNA binding DNA-directed DNA polymerase activity protein binding metal ion binding |
REV1 (S. cerevisiae) polh-1 (C. elegans) DNApol-eta (D. melanogaster) |
TOP1 | ENSG00000198900 |
AML* |
IRINOTECAN |
core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity |
TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster) |