USP7 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
USP7	ENSG00000187555	No diseases in record	No drugs in record	p53 binding cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding protein C-terminus binding transcription factor binding ubiquitin protein ligase binding	UBP15 (S. cerevisiae) Usp7 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)