UBR1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBR1	ENSG00000159459	No diseases in record	No drugs in record	zinc ion binding ligase activity ubiquitin protein ligase activity leucine binding metal ion binding ubiquitin-protein transferase activity transferase activity	UBR1 (S. cerevisiae) UBR2 (S. cerevisiae) ubr-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)