RTF1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RTF1	ENSG00000137815	No diseases in record	No drugs in record	transcription factor activity, RNA polymerase II transcription factor binding single-stranded DNA binding protein binding RNA polymerase II C-terminal domain phosphoserine binding DNA binding RNA binding histone methyltransferase activity (H3-K4 specific) mating type region replication fork barrier binding	RTF1 (S. cerevisiae) rtfo-1 (C. elegans) Rtf1 (D. melanogaster) CG31702 (D. melanogaster) CG31703 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)