SMC3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMC3	ENSG00000108055	No diseases in record	No drugs in record	chromatin binding microtubule motor activity protein binding ATP binding mediator complex binding protein heterodimerization activity nucleotide binding ATPase activity	SMC3 (S. cerevisiae) SMC3 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)