RABGEF1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RABGEF1	ENSG00000154710	No diseases in record	No drugs in record	DNA binding protein binding zinc ion binding Rab guanyl-nucleotide exchange factor activity Rab GTPase binding ubiquitin protein ligase activity	VPS9 (S. cerevisiae) rabx-5 (C. elegans) Rabex-5 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)