SMG1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMG1	ENSG00000157106	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding telomeric DNA binding metal ion binding molecular_function	TOR1 (S. cerevisiae) smg-1 (C. elegans) nonC (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)