H2AFY - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
H2AFY	ENSG00000113648	No diseases in record	No drugs in record	rDNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding core promoter sequence-specific DNA binding DNA binding protein binding double-stranded methylated DNA binding enzyme binding protein kinase binding protein serine/threonine kinase inhibitor activity chromatin DNA binding nucleosomal DNA binding transcription regulatory region DNA binding protein heterodimerization activity	HTA1 (S. cerevisiae) HTA2 (S. cerevisiae) His2A:CG31618 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)