MAPK14 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAPK14	ENSG00000112062	No diseases in record	No drugs in record	protein serine/threonine kinase activity MAP kinase activity MAP kinase kinase activity protein binding ATP binding enzyme binding protein phosphatase binding NFAT protein binding	HOG1 (S. cerevisiae) pmk-1 (C. elegans) p38b (D. melanogaster) p38a (D. melanogaster) p38c (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)