BRIP1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRIP1	ENSG00000136492	AML leukaemia breast	No drugs in record	DNA binding ATP-dependent DNA helicase activity protein binding ATP binding metal ion binding 4 iron, 4 sulfur cluster binding	CHL1 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)