XRCC3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XRCC3	ENSG00000126215	No diseases in record	No drugs in record	recombinase activity double-stranded DNA binding single-stranded DNA binding protein binding ATP binding DNA-dependent ATPase activity four-way junction DNA binding crossover junction endodeoxyribonuclease activity	RAD57 (S. cerevisiae) spn-B (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)