TOP1 - EHMT2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
EHMT2	ENSG00000238134	No diseases in record	No drugs in record	p53 binding protein binding zinc ion binding protein-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K9 specific) histone methyltransferase activity (H3-K27 specific) C2H2 zinc finger domain binding promoter-specific chromatin binding	SET2 (S. cerevisiae) G9a (D. melanogaster)