DRAP1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DRAP1	ENSG00000175550	No diseases in record	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding identical protein binding protein heterodimerization activity	BUR6 (S. cerevisiae) drap-1 (C. elegans) NC2alpha (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)