SLX1A - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SLX1A	ENSG00000132207	No diseases in record	No drugs in record	endodeoxyribonuclease activity protein binding crossover junction endodeoxyribonuclease activity 5'-flap endonuclease activity metal ion binding	SLX1 (S. cerevisiae) slx-1 (C. elegans) slx1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)