ARFGEF1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARFGEF1	ENSG00000066777	No diseases in record	No drugs in record	guanyl-nucleotide exchange factor activity ARF guanyl-nucleotide exchange factor activity protein binding myosin binding protein kinase A regulatory subunit binding GTPase activator activity	SEC7 (S. cerevisiae) Sec71 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)