Gene Name | Gene ID | Diseases | Drugs | GO terms | Orthologs |
---|---|---|---|---|---|
GEN1 | ENSG00000178295 |
No diseases in record |
No drugs in record |
DNA binding endodeoxyribonuclease activity crossover junction endodeoxyribonuclease activity metal ion binding |
RAD27 (S. cerevisiae) crn-1 (C. elegans) Gen (D. melanogaster) |
TOP1 | ENSG00000198900 |
AML* |
IRINOTECAN |
core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity |
TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster) |