REV3L - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
REV3L	ENSG00000009413	No diseases in record	No drugs in record	nucleotide binding DNA binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity metal ion binding 4 iron, 4 sulfur cluster binding	REV3 (S. cerevisiae) mus205 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)