EIF4G1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4G1	ENSG00000114867	No diseases in record	No drugs in record	translation initiation factor activity protein binding translation factor activity, RNA binding eukaryotic initiation factor 4E binding cadherin binding involved in cell-cell adhesion	TIF4631 (S. cerevisiae) TIF4632 (S. cerevisiae) ifg-1 (C. elegans) eIF4G2 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)