BUB1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BUB1	ENSG00000169679	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleotide binding kinase activity transferase activity histone kinase activity (H2A-S121 specific)	BUB1 (S. cerevisiae) MAD3 (S. cerevisiae) bub-1 (C. elegans) Bub1 (D. melanogaster) BubR1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)