AKT2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AKT2	ENSG00000105221	ovarian pancreatic	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)