SYVN1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SYVN1	ENSG00000162298	No diseases in record	No drugs in record	protein binding zinc ion binding ligase activity unfolded protein binding chaperone binding ATPase binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding	HRD1 (S. cerevisiae) sip3 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)