RAD51 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD51	ENSG00000051180	No diseases in record	No drugs in record	recombinase activity four-way junction DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding protein binding ATP binding protein C-terminus binding identical protein binding single-stranded DNA-dependent ATPase activity DNA polymerase binding endodeoxyribonuclease activity DNA-dependent ATPase activity nucleotide binding DNA binding ATPase activity Swi5-Sfr1 complex binding protein-DNA loading ATPase activity	RAD51 (S. cerevisiae) rad-51 (C. elegans) spn-A (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)