PIM1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIM1	ENSG00000137193	NHL	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding transcription factor binding manganese ion binding ribosomal small subunit binding mitochondrial light strand promoter anti-sense binding serine-type peptidase activity ATP-dependent peptidase activity nucleotide binding peptidase activity single-stranded DNA binding serine-type endopeptidase activity hydrolase activity DNA binding Ran guanyl-nucleotide exchange factor activity	PSK1 (S. cerevisiae) PSK2 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)