SEPT5 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SEPT5	ENSG00000184702	AML	No drugs in record	GTPase activity structural molecule activity protein binding GTP binding	CDC10 (S. cerevisiae) Sep1 (D. melanogaster) Sep4 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)