YWHAH - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
YWHAH	ENSG00000128245	No diseases in record	No drugs in record	actin binding insulin-like growth factor receptor binding protein binding sodium channel regulator activity enzyme binding protein domain specific binding glucocorticoid receptor binding ion channel binding protein heterodimerization activity	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) par-5 (C. elegans) ftt-2 (C. elegans) 14-3-3zeta (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)