TAF5 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF5	ENSG00000148835	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding transcription regulatory region DNA binding protein dimerization activity histone acetyltransferase activity ubiquitin binding protein complex scaffold activity chromatin binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly	TAF5 (S. cerevisiae) taf-5 (C. elegans) can (D. melanogaster) Taf5 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)