TDP1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TDP1	ENSG00000042088	No diseases in record	No drugs in record	double-stranded DNA binding single-stranded DNA binding exonuclease activity protein binding 3'-tyrosyl-DNA phosphodiesterase activity hydrolase activity nuclease activity 5'-tyrosyl-DNA phosphodiesterase activity phosphoric diester hydrolase activity	TDP1 (S. cerevisiae) gkt (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)