Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
TDP1
|
ENSG00000042088
|
No diseases in record
|
No drugs in record
|
double-stranded DNA binding
single-stranded DNA binding
exonuclease activity
protein binding
3'-tyrosyl-DNA phosphodiesterase activity
hydrolase activity
nuclease activity
5'-tyrosyl-DNA phosphodiesterase activity
phosphoric diester hydrolase activity
|
TDP1 (S. cerevisiae)
gkt (D. melanogaster)
|
TOP1
|
ENSG00000198900
|
AML*
|
IRINOTECAN
|
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
protein binding
isomerase activity
DNA topoisomerase activity
|
TOP1 (S. cerevisiae)
top-1 (C. elegans)
Top1 (D. melanogaster)
|