EIF4E - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4E	ENSG00000151247	No diseases in record	No drugs in record	RNA cap binding translation initiation factor activity protein binding enzyme binding eukaryotic initiation factor 4G binding repressing transcription factor binding	CDC33 (S. cerevisiae) ife-3 (C. elegans) ife-1 (C. elegans) ife-2 (C. elegans) ife-5 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)