MAP2K3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K3	ENSG00000034152	No diseases in record	No drugs in record	signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding protein kinase binding	PBS2 (S. cerevisiae) sek-1 (C. elegans) lic (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)