ERCC1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERCC1	ENSG00000012061	No diseases in record	No drugs in record	TFIID-class transcription factor binding damaged DNA binding single-stranded DNA binding protein binding protein C-terminus binding protein domain specific binding single-stranded DNA endodeoxyribonuclease activity protein heterodimerization activity	RAD10 (S. cerevisiae) ercc-1 (C. elegans) Ercc1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)