UBE2K - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBE2K	ENSG00000078140	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ATP binding ubiquitin protein ligase binding ubiquitin-ubiquitin ligase activity	UBC1 (S. cerevisiae) ubc-21 (C. elegans) ubc-22 (C. elegans) Ubc4 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)