KAT8 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KAT8	ENSG00000103510	No diseases in record	No drugs in record	histone acetyltransferase activity protein binding transcription factor binding acetyltransferase activity enzyme binding methylated histone binding metal ion binding histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K16 specific)	ESA1 (S. cerevisiae) mys-2 (C. elegans) mof (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)