CUL5 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CUL5	ENSG00000166266	No diseases in record	No drugs in record	ubiquitin-protein transferase activity receptor activity calcium channel activity protein binding ubiquitin protein ligase binding ubiquitin protein ligase activity	CDC53 (S. cerevisiae) cul-5 (C. elegans) Cul5 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)