MUS81 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MUS81	ENSG00000172732	No diseases in record	No drugs in record	DNA binding endodeoxyribonuclease activity protein binding metal ion binding 3'-flap endonuclease activity crossover junction endodeoxyribonuclease activity nuclease activity endonuclease activity enzyme inhibitor activity hydrolase activity	MUS81 (S. cerevisiae) mus81 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)