CHD3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHD3	ENSG00000170004	No diseases in record	No drugs in record	DNA binding ATP-dependent DNA helicase activity helicase activity histone deacetylase activity protein binding ATP binding zinc ion binding ATP-dependent helicase activity nucleosome-dependent ATPase activity nucleosome binding	CHD1 (S. cerevisiae) Mi-2 (D. melanogaster) Chd3 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)