PRKACB - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKACB	ENSG00000142875	No diseases in record	No drugs in record	magnesium ion binding protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein binding ATP binding kinase activity ubiquitin protein ligase binding	TPK1 (S. cerevisiae) TPK2 (S. cerevisiae) TPK3 (S. cerevisiae) kin-1 (C. elegans) Pka-C1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)