VRK1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VRK1	ENSG00000100749	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding protein kinase binding nucleosomal histone binding histone kinase activity (H3-S10 specific) histone kinase activity (H3-T3 specific)	HRR25 (S. cerevisiae) ball (D. melanogaster) CG8878 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)