PRKAA2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKAA2	ENSG00000162409	No diseases in record	No drugs in record	chromatin binding protein kinase activity protein serine/threonine kinase activity AMP-activated protein kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding histone serine kinase activity metal ion binding [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity [acetyl-CoA carboxylase] kinase activity	SNF1 (S. cerevisiae) aak-2 (C. elegans) AMPKalpha (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)