PRDX1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRDX1	ENSG00000117450	No diseases in record	No drugs in record	peroxidase activity protein binding thioredoxin peroxidase activity identical protein binding cadherin binding involved in cell-cell adhesion	TSA1 (S. cerevisiae) TSA2 (S. cerevisiae) Jafrac1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)