EIF2B1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF2B1	ENSG00000111361	No diseases in record	No drugs in record	protein binding identical protein binding S-methyl-5-thioribose-1-phosphate isomerase activity translation initiation factor activity guanyl-nucleotide exchange factor activity	GCN3 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)