SGK1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SGK1	ENSG00000118515	Nodular lymphocyte predominant Hodgkin lymphoma	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity calcium channel regulator activity protein binding ATP binding potassium channel regulator activity sodium channel regulator activity chloride channel regulator activity	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) sgk-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)