ATRX - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ATRX	ENSG00000085224	pancreatic neuroendocrine tumours paediatric GBM	No drugs in record	DNA binding DNA helicase activity chromatin binding helicase activity protein binding ATP binding DNA translocase activity methylated histone binding histone binding metal ion binding chromo shadow domain binding	RDH54 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)