PRKAR1A - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKAR1A	ENSG00000108946	papillary thyroid myxoma endocrine	No drugs in record	cAMP-dependent protein kinase inhibitor activity protein binding cAMP-dependent protein kinase regulator activity cAMP binding ubiquitin protein ligase binding protein kinase A catalytic subunit binding	BCY1 (S. cerevisiae) kin-2 (C. elegans) Pka-R1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)