NUP98 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NUP98	ENSG00000110713	AML	No drugs in record	RNA binding transporter activity nucleocytoplasmic transporter activity protein binding nuclear localization sequence binding structural constituent of nuclear pore	NUP145 (S. cerevisiae) npp-10 (C. elegans) Nup98-96 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)